Fecha/hora: 09/05/2024 14:41:11

Biblioteca(s): 	INIA Las Brujas.	
Fecha corriente: 	30/05/2019	
Fecha de la última actualización: 	20/04/2020	
Autoria: 	ABREO, E.; ALTIER, N.	
Afiliación: 	EDUARDO RAUL ABREO GIMENEZ, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; NORA ADRIANA ALTIER MANZINI, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay.	
Título: 	Pangenome of Serratia marcescens strains from nosocomial and environmental origins reveals different populations and the links between them.	
Año de publicación: 	2019	
Fuente/Imprenta: 	Scientific Reports, 1 December 2019, Volume 9, Issue 1, Article number 46. OPEN ACCESS. Doi: https://doi.org/10.1038/s41598-018-37118-0	
ISSN: 	2045-2322	
DOI: 	10.1038/s41598-018-37118-0	
Idioma: 	Inglés	
Notas: 	Article history: Received: 25 July 2018 // Accepted: 30 November 2018 // Published online: 10 January 2019. 
Author Contributions: Eduardo Abreo and Nora Altier designed the study, E.A. performed the genomic analysis and wrote the manuscript, E.A. and N.A. analyzed the results. Both authors reviewed the manuscript.	
Contenido: 	ABSTRACT.
Serratia marcescens is a Gram-negative bacterial species that can be found in a wide range of environments like soil, water and plant surfaces, while it is also known as an opportunistic human pathogen in hospitals and as a plant growth promoting bacteria (PGPR) in crops. We have used a pangenome-based approach, based on publicly available genomes, to apply whole genome multilocus sequence type schemes to assess whether there is an association between source and genotype, aiming at differentiating between isolates from nosocomial sources and the environment, and between strains reported as PGPR from other environmental strains. Most genomes from a nosocomial setting and environmental origin could be assigned to the proposed nosocomial or environmental MLSTs, which is indicative of an association between source and genotype. The fact that a few genomes from a nosocomial source showed an environmental MLST suggests that a minority of nosocomial strains have recently derived from the environment. PGPR strains were assigned to different environmental types and clades but only one clade comprised strains accumulating a low number of known virulence and antibiotic resistance determinants and was exclusively from environmental sources. This clade is envisaged as a group of promissory MLSTs for selecting prospective PGPR strains. 
© 2019, The Author(s).	
Palabras-Clave: 	ANTIBIOTIC RESISTANCE; CLADISTICS; GENOME; GENOTYPE; SERRATIA MARCESCENS; VIRULENCE.	
Categoría del tema: 	H20 Enfermedades de las plantas	
URL: 	http://www.ainfo.inia.uy/digital/bitstream/item/12716/1/Abreo-Altier.-2019.-Scientific-Reports.-10.1038-s41598-018-37118-0.pdf
https://www.nature.com/articles/s41598-018-37118-0.pdf	
Registro original: 	INIA Las Brujas (LB)	
Ejemplares: 	LB - (101831-1) - PXI - AP - DD - PP/SCIENTIFIC REPORTS/2019 -  -  - DIS